Freeze granulation gives the possibility to granulate nanoparticles achieving granules with high degree of homogeneity which are easily re-dispersed (if applicable) in a liquid or dis-integrated at a pressing operation. This is owing to the week inter-particle bonding compare to what is obtained in conventional drying. Consequently, the nanosized material properties will be preserved, i.e. nano will still be nano. Freeze-drying also prevents oxidation of metals or non-oxide materials as conventional drying do not, especially critical for nanopowders.
Nanoparticles (Nanosuspensions) can be granulated and dried into a powder and then re-dispersed to nanoparticles again avoiding agglomeration (aggregates) of nanoparticles, which is not possible with other granulation methods like spray drying.