Freeze Granulation is being used for drying of pharmaceuticals and drugs, and for drying of biomaterials like proteins, enzymes and fine chemicals. Improved solubility (re-disperse) from low-temperature drying is an important advantage.
Freeze granulation, as opposed to spray drying, has been shown to produce protein particles with light and porous characteristics, which offered powders with superior aerosol performance due to favorable aerodynamic properties – protein aerosol powders.